Structure of PDB 8w49 Chain A

Receptor sequence
>8w49A (length=411) Species: 10090 (Mus musculus) [Search protein sequence]
RKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDAT
NDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNI
LGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKV
EITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALS
KGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLID
DMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKT
VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTEL
SFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLG
ENLKAKLAQAK
3D structure
PDB8w49 mouse isocitrate dehydrogenase with isocitrate and magnesium
ChainA
Resolution1.77 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A T75 T77 N96 L288 H309 G310 T311 V312 T313 H315 T327 N328 T73 T75 N94 L286 H307 G308 T309 V310 T311 H313 T325 N326
BS02 NAP A D253 Q257 K260 D251 Q255 K258
External links
PDB RCSB:8w49, PDBe:8w49, PDBj:8w49
PDBsum8w49
PubMed
UniProtO88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic (Gene Name=Idh1)

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