Structure of PDB 8w31 Chain A

Receptor sequence

>8w31A (length=235) Species: 10116 (Rattus norvegicus) [Search protein sequence]

SSFFVYCKGPCHKVQPGKLRVQCGTCRQATLTLAQGPSCWDDVLIPNRMS
GECQSPDCPGTRAEFFFKCGAHPTSDKDTSVALNLITNNSRSIPCIACTD
VRNPVLVFQCNHRHVICLDCFHLYCVTRLNDRQFVHDAQLGYSLPCVAGC
PNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLP
EQGQRKVTCEGGNGLGCGFVFCRDCKEAYHEGECD

3D structure

PDB

8w31 Activation of Parkin by a Molecular Glue

Chain

Resolution

2.5 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	ZN	A	C150 C154 C212 H215	C7 C11 C69 H72
BS02	ZN	A	C253 H257 C289 C293	C110 H114 C146 C150
BS03	ZN	A	C365 C368 H373	C222 C225 H230
BS04	ZN	A	C166 C169 C196 C201	C23 C26 C53 C58
BS05	ZN	A	C238 C241 C260 C263	C95 C98 C117 C120
BS06	ZN	A	C332 C337 C352 C360	C189 C194 C209 C217
BS07	A1AE9	A	S144 F146 L162 L176 P180 S181 C182 F208	S1 F3 L19 L33 P37 S38 C39 F65

External links

PDB	RCSB:8w31, PDBe:8w31, PDBj:8w31
PDBsum	8w31
PubMed
UniProt	Q9JK66\|PRKN_RAT E3 ubiquitin-protein ligase parkin (Gene Name=Prkn)

[Back to BioLiP]