Structure of PDB 8w0o Chain A

Receptor sequence
>8w0oA (length=259) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MYPDLKGKVVAITGAASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKE
EVIKAGGEAVVVQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVP
SHEMPLKDWDKVIGTNLTGAFLGSREAIKYFVENDIKGNVINMSSVHEVI
PWPLFVHYAASKGGMKLMTKTLALEYAPKGIRVNNIGPGAINTTINAEKF
ADPKQKADVESMIPMGYIGEPEEIAAVAAWLASKEASYVTGITLFADGGM
TLYPSFQAG
3D structure
PDB8w0o Enhancing the Imine Reductase Activity of a Promiscuous Glucose Dehydrogenase for Scalable Manufacturing of a Chiral Neprilysin Inhibitor Precursor
ChainA
Resolution1.66 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G14 S17 G18 L19 Y39 Q43 D65 V66 N92 A93 G94 M143 Y158 K162 P188 G189 I191 T193 G14 S17 G18 L19 Y39 Q43 D65 V66 N92 A93 G94 M143 Y158 K162 P188 G189 I191 T193
Gene Ontology
Molecular Function
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0047936 glucose 1-dehydrogenase [NAD(P)+] activity

View graph for
Molecular Function
External links
PDB RCSB:8w0o, PDBe:8w0o, PDBj:8w0o
PDBsum8w0o
PubMed
UniProtM9TFE3

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