Structure of PDB 8w06 Chain A

Receptor sequence

>8w06A (length=250) Species: 32630 (synthetic construct) [Search protein sequence]

HMARKFFVGGNWKMNGTIESIKSLVETLNNAELDDNTEVVVAPPAIYLPL
VRQSLRKDIQVAAQNCYTKASGAFTGEISAEMLKDLGIPWVILGHSERRQ
IFGESDEFVAEKTKYALDNGLKVILCIGETLEEREAGKTMDVVTRQLKAI
ADKISESDWSKVVIAYEPVWAIGTGKVATPEQAQEVHAEIRKWLAENVSA
EVAESTRIIYGGSVNGGNCKELAKQPDIDGFLVGGASLKPEFVDIINARQ

3D structure

PDB

8w06 Stable monomers in the ancestral sequence reconstruction of the last opisthokont common ancestor of dimeric triosephosphate isomerase.

Chain

Resolution

2.06 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	PGH	A	N10 K12 H94 E166 I171 G172 G211 S212 L231 G233 G234	N11 K13 H95 E167 I172 G173 G212 S213 L232 G234 G235

External links

PDB	RCSB:8w06, PDBe:8w06, PDBj:8w06
PDBsum	8w06
PubMed	39145435

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