Structure of PDB 8vy4 Chain A

Receptor sequence

>8vy4A (length=216) Species: 10090 (Mus musculus) [Search protein sequence]

PSVEESEGGLFKPTDTLTLTCTVSGFSLSSNAISWVRQAPGKGLEWIGFV
AVTGYSYYASWAKSRSTITRNTGLNTVTLKMTSLTAADTATYFCARIGIG
IDFNIWGPGTLVTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFP
EPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNV
AHPASSTKVDKKIEPR

3D structure

PDB

8vy4 Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy.

Chain

Resolution

1.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	F49 A51 V52 R96 I99	F49 A51 V52 R96 I99

External links

PDB	RCSB:8vy4, PDBe:8vy4, PDBj:8vy4
PDBsum	8vy4
PubMed	38962811

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