Structure of PDB 8vxa Chain A

Receptor sequence
>8vxaA (length=1139) Species: 562 (Escherichia coli) [Search protein sequence]
MPATADEIIEAIKEASAVGFRGRLIARGQARSVIWRDGDLPPDAPEFSAL
LSQDLQGYAYALIDLGLRLRELNGDDAYARIAFEQAGTALESAIAKGKRD
SRDTDFHFVMAAASYHLAHLSARAYSLLAMVGQDDNFSPIERALTQLIRR
DLRTLRDNALGFRLRGDDLALTDAYMSAISLYLLAVERGESRLLSRAIEK
LRISLSICAQFNMLPQWWLNFITIHLLSDLWSDTFHERLPLVPVGGDAAE
WPALRELFIALLQRRPRAEIDLWPSQREAAGRSVNDNDDLVVSLPTSAGK
TRIAELCILRCLAGGKRVVFITPLRALSAQTEATLSRTFGPLGKTISMLY
GSIGVSGMDEDAIRQRDIVVATPEKLDFALRNDPSIINDVGLFIFDEGHM
IGADEREVRYEVQIQRLLRRQDADTRRIVCLSAILPDGEQLDDFAGWLRR
DKPGGPIKNNWRPTRLQFGEVIWSAPAGRLNLSVGYEAAWVSRFIVSRQP
PKVKLPNKKQRTKMFPSDNKELCLATAWRLIEDGQTVLIYCPLRRSVEPF
AETIVDLHQRGLLPSLFDAAPDILDTAISLGEEWLGAHSPILACLRLGVA
LHHGALPTAYRKEIERLLRDGVLKVTISSPTLAQGLNLSATAIVMHSLHR
NRELIKVSEFRNVIGRAGRAYVDVEGLVIYPIFDKVNKRQTNWHTLTSDT
GAREMESGLIQLVCVLLIRMHTRLGGDLKALTEYVTNNAVAWEFPEIMTE
SPQERDIAQAIWEKQLSTLDTAILSLLGENDIPDDQIETALDDILQSSLW
QRSLQRYRDENERILLKSGLLSRSRYIWQRSTAAGRRGYFLSGVGLTTGL
RLDAIAAKANQLLIDANAAIMGGDAEEAIAAITALAEEVFTFYPFIPDPL
PGDWRGILRSWLLGEPMTNVANTQASETLQFVENGLVYRLPWAMEAIRVR
ATANGDLIGDTDTTLDDYELGFAVAAVETGTLSRSSSLLIQAGFSSRLAA
IKVVTDTTADFQSGQELRRWLNSEEVISHTDNHDWPTPETRVMWLEFLGS
LSPKGSQVWSRHRYNGMVDWRDTPAVIGTPLQLYTVDGIHHVLADDGTPL
GSINGRINTNRRGLLRVEVDDENGRAMFDYLGPDDFIST
3D structure
PDB8vxa Hachiman is a genome integrity sensor
ChainA
Resolution2.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A L359 R360 S387 E409 D439 R441 N542 K544 K548 R579 R595 Q669 R685 N686 E694 Y973 L324 R325 S352 E374 D404 R406 N507 K509 K513 R544 R560 Q634 R650 N651 E659 Y938
BS02 dna A H681 H684 R687 K723 R724 H646 H649 R652 K688 R689
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:8vxa, PDBe:8vxa, PDBj:8vxa
PDBsum8vxa
PubMed38464307
UniProtA0A426EXV0

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