Structure of PDB 8vuw Chain A

Receptor sequence
>8vuwA (length=311) Species: 556 (Dickeya chrysanthemi) [Search protein sequence]
PVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVEN
TQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSF
SNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEW
WIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFIL
PLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILGRLPYTT
YIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRSRLAFPLGFLA
IGCVLVIRFFT
3D structure
PDB8vuw Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
ChainA
Resolution3.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PGW A Q264 I267 A268 G271 F274 F304 Q254 I257 A258 G261 F264 F294
BS02 DHL A E77 E131 Y175 H177 F188 E67 E121 Y165 H167 F178
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8vuw, PDBe:8vuw, PDBj:8vuw
PDBsum8vuw
PubMed36385237
UniProtP0C7B7|ELIC_DICCH Cys-loop ligand-gated ion channel

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