Structure of PDB 8vta Chain A

Receptor sequence

>8vtaA (length=404) Species: 154 (Spirochaeta thermophila) [Search protein sequence]

TYTLVWKVWILAVTLYYAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLAFESRRTSGRKPTLLAPSRLPDLLAALPLDLLVFALHLPSPLSLLSL
VRLLKLISVQASATRILSYRINPALLRLLSLVGFILLAAHGIACGWMSLQ
PPSENPAGTRYLSAFYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAA
MYGLVIGNIASLVSKLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEY
FDYLWETRRGYEEREVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEF
IRDIILHLEPVIYGPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAI
LSEGQFFGEMALILRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAA
QIQE

3D structure

PDB

8vta PIP2 inhibits pore opening of a CNG channel

Chain

Resolution

3.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CMP	A	V348 F366 G367 E368 M369 R377 T378	V339 F357 G358 E359 M360 R368 T369
BS02	PT5	A	L134 L138	L125 L129

External links

PDB	RCSB:8vta, PDBe:8vta, PDBj:8vta
PDBsum	8vta
PubMed
UniProt	G0GA88

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