Structure of PDB 8vt9 Chain A

Receptor sequence

>8vt9A (length=406) Species: 154 (Spirochaeta thermophila) [Search protein sequence]

TYTLVWKVWILAVTLYYAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLAFESRRTSGRKPTLLAPSRLPDLLAALPLDLLVFALHLPSPLSLLSL
VRLLKLISVQRSATRILSYRINPALLRLLSLVGFILLAAHGIACGWMSLQ
PPSENPAGTRYLSAFYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAA
MYGLVIGNIASLVSKLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEY
FDYLWETRRGYEEREVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEF
IRDIILHLEPVIYGPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAI
LSEGQFFGEMALILRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAA
QIQELA

3D structure

PDB

8vt9 PIP2 inhibits pore opening of a CNG channel

Chain

Resolution

2.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CMP	A	V348 A358 G367 M369 R377 T378 A379	V339 A349 G358 M360 R368 T369 A370
BS02	PT5	A	R120 R124	R111 R115
BS03	PT5	A	I130 L134 L138 L225	I121 L125 L129 L216

External links

PDB	RCSB:8vt9, PDBe:8vt9, PDBj:8vt9
PDBsum	8vt9
PubMed
UniProt	G0GA88

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