Structure of PDB 8vmf Chain A

Receptor sequence

>8vmfA (length=355) Species: 10090 (Mus musculus) [Search protein sequence]

KVSRDSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSG
ELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLN
LVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICH
RDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIF
GATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTRE
QIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARL
TPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIP
PHARH

3D structure

PDB

8vmf Structural and functional effects of phosphopriming and scaffolding in the kinase GSK-3 beta.

Chain

Resolution

2.5 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	F229 V263 D264 L266 Y288 F291 K292 F293 P294	F200 V234 D235 L237 Y259 F262 K263 F264 P265
BS02	peptide	A	R92 F93 K94 R180 K205 V214 Y216 I217	R63 F64 K65 R151 K176 V185 Y187 I188
BS03	MG	A	N186 D200	N157 D171
BS04	AF3	A	G65 S66 D181 K183 D200	G36 S37 D152 K154 D171
BS05	ADP	A	G65 G68 A83 K85 Y134 V135 L188 D200	G36 G39 A54 K56 Y105 V106 L159 D171

External links

PDB	RCSB:8vmf, PDBe:8vmf, PDBj:8vmf
PDBsum	8vmf
PubMed	39226374
UniProt	Q9WV60\|GSK3B_MOUSE Glycogen synthase kinase-3 beta (Gene Name=Gsk3b)

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