Structure of PDB 8vjp Chain A

Receptor sequence
>8vjpA (length=152) Species: 9606 (Homo sapiens) [Search protein sequence]
DELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQ
RNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFG
AFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV
ED
3D structure
PDB8vjp Histidine-Covalent Stapled Alpha-Helical Peptides Targeting hMcl-1.
ChainA
Resolution1.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V220 H224 M231 H252 V253 D256 G262 R263 T266 V49 H53 M60 H81 V82 D85 G91 R92 T95
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:8vjp, PDBe:8vjp, PDBj:8vjp
PDBsum8vjp
PubMed38695666
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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