Structure of PDB 8vhh Chain A

Receptor sequence
>8vhhA (length=389) Species: 2336 (Thermotoga maritima) [Search protein sequence]
KGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGR
PTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTR
IIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAK
VVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQ
KVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVE
AGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDY
SGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALA
YLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
3D structure
PDB8vhh A combinatorially complete epistatic fitness landscape in an enzyme active site.
ChainA
Resolution2.15 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A H82 K83 Q110 S186 G229 G230 S231 N232 G298 E345 S368 H81 K82 Q109 S185 G228 G229 S230 N231 G297 E344 S367
External links
PDB RCSB:8vhh, PDBe:8vhh, PDBj:8vhh
PDBsum8vhh
PubMed39074291
UniProtP50909|TRPB1_THEMA Tryptophan synthase beta chain 1 (Gene Name=trpB1)

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