Structure of PDB 8vep Chain A

Receptor sequence
>8vepA (length=324) Species: 485 (Neisseria gonorrhoeae) [Search protein sequence]
ALSLDQRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALVNTPGRN
RAVTDMIEPGSVMKPFPIAKALDSGKVDTTDTFNTLPYKIGPATVQDTHV
YPTLDVRGIMQKSSNVGTSKLSAMFTPKEMYDFYHDLGVGVRMHSGFPGE
SAGVLRNWRKWRPIEQATMSFGYGLQLSLLQLARAYTVLTHDGELLPVSF
EKQAVAPKGKRVIKASTAKKVRELMVSVTEAGGSGIAGAVDGFDVGAKTG
TARKLVNGRYVDYKHVATFIGFAPAKNPRVIVAVTIDEPTANGYYSGVVT
GPVFKQVMGGSLNILGVSPTKPLT
3D structure
PDB8vep Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant Neisseria gonorrhoeae H041.
ChainA
Resolution2.002 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.16.4: serine-type D-Ala-D-Ala carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JPP A S310 T347 S362 N364 Y422 T498 G499 T500 R502 Y509 Y544 S61 T98 S113 N115 Y173 T249 G250 T251 R253 Y260 Y295
Gene Ontology
Molecular Function
GO:0008658 penicillin binding

View graph for
Molecular Function
External links
PDB RCSB:8vep, PDBe:8vep, PDBj:8vep
PDBsum8vep
PubMed38446051
UniProtF2Z7K9

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