Structure of PDB 8vcx Chain A

Receptor sequence

>8vcxA (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]

IVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLFR
RFRRFDPQFALTNIAVLKHNLNCVIKRSNSTAATNEVPEVTVFSKSPVTL
GQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKIS
YLTFLPSADEIYDCKVEHWGLDEPLLKHWEP

3D structure

PDB

8vcx A structural basis of T cell cross-reactivity to a native and spliced self-antigens presented by HLA-DQ8

Chain

Resolution

2.59 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y9 R52 R53 F54 F58 N62 H68 N69 C72 R76	Y9 R53 R54 F55 F59 N63 H69 N70 C73 R77

External links

PDB	RCSB:8vcx, PDBe:8vcx, PDBj:8vcx
PDBsum	8vcx
PubMed	39074636
UniProt	Q30069

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