Structure of PDB 8v5n Chain A

Receptor sequence
>8v5nA (length=182) Species: 8355 (Xenopus laevis) [Search protein sequence]
RDCERFKFFCPKCGTENIYDNVFDGSGLQIEPGLKRCSKPECDASPLDYV
IQVHNKLLLDIRRYIKKYYSGWLVCEEKTCQNRTRRLPLSFSRNGPICQA
CSKATLRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKLFQ
ESENQYKKLKSTVDQVLSRSGYSEVNLSKLFQ
3D structure
PDB8v5n A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase
ChainA
Resolution8.56 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1280 C1283 C1307 C1312 C10 C13 C37 C42
BS02 ZN A C1345 C1350 C1368 C1371 C75 C80 C98 C101
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication
GO:1902975 mitotic DNA replication initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:8v5n, PDBe:8v5n, PDBj:8v5n
PDBsum8v5n
PubMed38491139
UniProtQ9DE46|DPOLA_XENLA DNA polymerase alpha catalytic subunit (Gene Name=pola1)

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