Structure of PDB 8v2t Chain A

Receptor sequence
>8v2tA (length=191) Species: 357348 (Burkholderia pseudomallei 1106a) [Search protein sequence]
LTYITNSIAEAQRVMAAMLADERLLATVRKVADACIASIAQGGKVLLAGN
GGSAADAQHIAGEFVSRFAFDRPGLPAVALTTDTSILTAIGNDYGYEKLF
SRQVQALGNEGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGE
MRELCDLLLEVPSADTPKIQEGHLVLGHIVCGLVEHSIFGK
3D structure
PDB8v2t Potentiating Activity of GmhA Inhibitors on Gram-negative Bacteria
ChainA
Resolution1.402 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.1.28: D-sedoheptulose-7-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XLR A N55 G57 S123 T124 S125 S128 T171 Q175 N50 G52 S118 T119 S120 S123 T166 Q170
BS02 ZN A H64 E68 H183 H59 E63 H178
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008968 D-sedoheptulose 7-phosphate isomerase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0097367 carbohydrate derivative binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0045227 capsule polysaccharide biosynthetic process
GO:1901135 carbohydrate derivative metabolic process
GO:2001061 D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:8v2t, PDBe:8v2t, PDBj:8v2t
PDBsum8v2t
PubMed38598312
UniProtQ93UJ2|GMHA_BURPS Phosphoheptose isomerase (Gene Name=gmhA)

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