Structure of PDB 8v2i Chain A

Receptor sequence

>8v2iA (length=437) [Search protein sequence]

MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSGGGDDSFNTFFS
ETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYA
RGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLM
ERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMV
DNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTE
FQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVK
CDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVG
INYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAF
VHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVE

3D structure

PDB

8v2i Cryo-EM structures of human a1B/bI+bIVb microtubules shed light on isoform specific assembly

Chain

Resolution

Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GTP	A	Q11 A12 Q15 D98 A99 N101 S140 G143 G144 T145 I171 T179 N206 Y224 N228	Q11 A12 Q15 D94 A95 N97 S136 G139 G140 T141 I167 T175 N202 Y220 N224

External links

PDB	RCSB:8v2i, PDBe:8v2i, PDBj:8v2i
PDBsum	8v2i
PubMed

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