Structure of PDB 8v05 Chain A

Receptor sequence
>8v05A (length=426) Species: 10090 (Mus musculus) [Search protein sequence]
GDLHLFGPNQRPAPCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGL
LAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLQQLQALAPRGVKVR
IAVSKPNGPLADLQSLLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYL
GSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPST
WPRSFDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNV
VDSARSFIYIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLI
SCWGHSDPSMRSFLLSLAALHDNHTHSDIQVKLFVVPTDESQARIPYARV
NHNKYMVTERASYIGTSNWSGSYFTETAGTSLLVTQNGHGGLRSQLEAVF
LRDWESPYSHDLDTSANSVGNACRLL
3D structure
PDB8v05 Crystal structures of exonucleases PLD3 and PLD4
ChainA
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.16.1: spleen exonuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MAN A T99 T100 S101 T37 T38 S39
BS02 CYS A C280 G283 T284 P285 C218 G221 T222 P223
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:8v05, PDBe:8v05, PDBj:8v05
PDBsum8v05
PubMed38537643
UniProtO35405|PLD3_MOUSE 5'-3' exonuclease PLD3 (Gene Name=Pld3)

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