Structure of PDB 8uyi Chain A

Receptor sequence
>8uyiA (length=369) Species: 121224 (Pediculus humanus corporis) [Search protein sequence]
KDDELEGICWEIREAVSVEQLQAANLDELDLGEPIAKGCNAVVYSAKLKH
QLAVKMMFNYDVESNSTAILKAMYRETVPAMSYFFNFKIRLPPHPNIVRM
YSVFADRNMSLFLVMKRYDCTLKEYLRDKTPNMRSSILLLSQLLEAVAHM
NIHNISHRDLKSDNILVDLSEGDAYPTIVITDFGCCLCDKQNGLVIPYRS
EDQDKGGNRALMAPEIANAKPGTFSWLNYKKSDLWAVGAIAYEIFNIDNP
FYKLLSKSYKEEDLPELPDTIPFIIRNLVSNMLSRSTNKRLDCDVAATVA
QLYLWAPSSWLKENYTLPNSNEIIQWLLCLSSKVLCRRSLPEYELIASFL
RRVRLHLVRKGLKWIQELH
3D structure
PDB8uyi Interaction of PINK1 with nucleotides and kinetin.
ChainA
Resolution3.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A A166 K193 M290 K291 R292 Y293 T296 L341 D357 A36 K55 M115 K116 R117 Y118 T121 L166 D182
BS02 MG A N339 D357 N164 D182
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8uyi, PDBe:8uyi, PDBj:8uyi
PDBsum8uyi
PubMed38241364
UniProtE0W1I1|PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial (Gene Name=Pink1)

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