Structure of PDB 8uyh Chain A

Receptor sequence
>8uyhA (length=375) Species: 121224 (Pediculus humanus corporis) [Search protein sequence]
SGLLTKDDELEGICWEIREAVSVEQLQAANLDELDLGEPIAKGCNAVVYS
AKLKHQLAVKMMFNYDVESNSTAILKAMYRETVPAMSYFFNFKIRLPPHP
NIVRMYSVFADRNMSLFLVMKRYDCTLKEYLRDKTPNMRSSILLLSQLLE
AVAHMNIHNISHRDLKSDNILVDLSEGDAYPTIVITDFGCCLCDKQNGLV
IPYRSEDQDKGGNRALMAPEIANAKPGTFSWLNYKKSDLWAVGAIAYEIF
NIDNPFYKLLSKSYKEEDLPELPDTIPFIIRNLVSNMLSRSTNKRLDCDV
AATVAQLYLWAPSSWLKENYTLPNSNEIIQWLLCLSSKVLCRSLPEYELI
ASFLRRVRLHLVRKGLKWIQELHIY
3D structure
PDB8uyh Interaction of PINK1 with nucleotides and kinetin.
ChainA
Resolution2.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A K193 M290 K291 Y293 L341 D357 K60 M120 K121 Y123 L171 D187
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8uyh, PDBe:8uyh, PDBj:8uyh
PDBsum8uyh
PubMed38241364
UniProtE0W1I1|PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial (Gene Name=Pink1)

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