Structure of PDB 8uvu Chain A

Receptor sequence
>8uvuA (length=379) Species: 7091 (Bombyx mori) [Search protein sequence]
TPCLVGGAHAFILKISSFCGLAPLRFEPRSQEYAVTISKGKCFYSYILVT
FLVICTIYGLVAEIGVGVEKSVRMSSRMSQVVSACDILVVAVTAGVGVYG
APARMRTMLSYMENIVAVDRELGRHHSAATERKLCALLLLILLSFTILLV
DDFCFYAMQAGKTGRQWEIVTNYAGFYFLWYIVMVLELQFAFTALSLRAR
LKLFNEALNVTASQCLQVPPCEAVGRLSRMRCTLCEVTRHIADGYGLPLV
IILMSTLLHLIVTPYFLIMEIIVSTHRLHFLVLQFLWCTTHLIRMLVVVE
PCHYTIREGKRTEDILCRLMTLAPHGGVLSSRLEVLSRLLMLQNISYSPL
GMCTLDRPLMVTVLGAVTTYLVILIQFQR
3D structure
PDB8uvu The molecular basis of sugar detection by an insect taste receptor.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BDF A R86 D99 D165 F189 T330 Q351 W354 R73 D86 D152 F176 T263 Q284 W287
BS02 FRU A R86 D99 F189 W193 T330 F333 Q351 W354 H358 R73 D86 F176 W180 T263 F266 Q284 W287 H291
Gene Ontology
Molecular Function
GO:0099094 ligand-gated monoatomic cation channel activity
GO:0170021 ionotropic taste receptor activity
Biological Process
GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste
GO:0007165 signal transduction
GO:0007635 chemosensory behavior
GO:0008049 male courtship behavior
GO:0050909 sensory perception of taste
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030424 axon
GO:0030425 dendrite
GO:0043025 neuronal cell body

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8uvu, PDBe:8uvu, PDBj:8uvu
PDBsum8uvu
PubMed38447670
UniProtB3GTD7

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