Structure of PDB 8usw Chain A

Receptor sequence
>8uswA (length=726) Species: 9606 (Homo sapiens) [Search protein sequence]
KIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQM
ALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTR
MSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEGR
AAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSAS
EDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGILGLQLING
KNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRV
LMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIP
NDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEF
TVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTY
EVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERA
QYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVA
VMLYLSARILGMVWAGFAMIIVASYTANLAAFLVVDRPEERITGINDPRL
RNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVR
DNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNV
SLSILKSHENGFMEDLDKTWVRYQEC
3D structure
PDB8usw Structure and function of GluN1-3A NMDA receptor excitatory glycine receptor channel
ChainA
Resolution4.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DQC A Q405 F484 L517 T518 S688 W731 D732 V735 Q381 F460 L493 T494 S616 W659 D660 V663
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8usw, PDBe:8usw, PDBj:8usw
PDBsum8usw
PubMed38598639
UniProtQ05586|NMDZ1_HUMAN Glutamate receptor ionotropic, NMDA 1 (Gene Name=GRIN1)

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