Structure of PDB 8urk Chain A

Receptor sequence

>8urkA (length=249) Species: 95486 (Burkholderia cenocepacia) [Search protein sequence]

LPSGIELHNRDFLTDAAHLPDASIDLIVADPPYGLGKDYGNDSDKRSGDD
FLAWTREWLELAIPKLKPSGSMYIFCTWQYAPEIFSFLKTQLTMVNEIIW
DRRVPSMGGTTRRFTSVHDNIGFFAVSRAYYFDLDPVRIPYDADTKKARS
RKLFEGSKWLEMGYNPKDVWSVSRLHRQHAERVDHPTQKPLEIIERMVLA
SCPPGGRVLDPFMGSGTTAVACARQGRDFVGYEINESYCAIAHERVNAL

3D structure

PDB

8urk Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.

Chain

Resolution

2.11 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	P60 P61 Y62 L64 K66 Y68 D73 T106 W107 V133 S135 M136 G137 T139 R141 R142 S145 D148 R203 H205 R206 R211 T216 K218	P31 P32 Y33 L35 K37 Y39 D44 T77 W78 V104 S106 M107 G108 T110 R112 R113 S116 D119 R174 H176 R177 R182 T187 K189
BS02	dna	A	R132 V133 P134 M136 G137 G138 T139 T144 S202 H205 Q207 H208 A209	R103 V104 P105 M107 G108 G109 T110 T115 S173 H176 Q178 H179 A180
BS03	dna	A	R157 R180 F183	R128 R151 F154
BS04	dna	A	R167 Y170 R178 R180 F183 K187 W188 N194 K196	R138 Y141 R149 R151 F154 K158 W159 N165 K167
BS05	FRU	A	W107 Q108	W78 Q79
BS06	SFG	A	D40 D59 Y68 S72 H214 T216 Q217 K218 F241 M242 S244 T246 Y261 E262 I263 Y267	D11 D30 Y39 S43 H185 T187 Q188 K189 F212 M213 S215 T217 Y232 E233 I234 Y238

External links

PDB	RCSB:8urk, PDBe:8urk, PDBj:8urk
PDBsum	8urk
PubMed	39244607
UniProt	A0A8I1DKW0

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