Structure of PDB 8urf Chain A

Receptor sequence
>8urfA (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
CPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQ
HTNPFNTWIGLTDSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSE
DCVEVQPDGRWNDDFCLQVYRWVCEKRR
3D structure
PDB8urf Targeted protein degradation systems to enhance Wnt signaling.
ChainA
Resolution1.9 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D239 N266 E276 D277 D63 N90 E100 D101
BS02 CA A Q263 D265 E276 N288 D289 Q87 D89 E100 N112 D113
BS03 CA A V214 N216 E220 E301 V38 N40 E44 E125
External links
PDB RCSB:8urf, PDBe:8urf, PDBj:8urf
PDBsum8urf
PubMed38847394
UniProtP07307|ASGR2_HUMAN Asialoglycoprotein receptor 2 (Gene Name=ASGR2)

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