Structure of PDB 8umo Chain A

Receptor sequence
>8umoA (length=278) Species: 10090 (Mus musculus) [Search protein sequence]
SPHSLRYFTTAVSRPGLGEPRFIIVGYVDDTQFVRFDSDAENPRMEPRAR
WIEQEGPEYWERETWKARDMGRNFRVNLRTLLGYYNQSNDESHTLQWMYG
CDVGPDGRLLRGYCQEAYDGQDYISLNEDLRSWTANDIASQISKHKSEAV
DEAHQQRAYLQGPCVEWLHRYLRLGNETLQRSDPPKAHVTHHPRSEDEVT
LRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWAAVVVP
LGKEQYYTCHVYHEGLPEPLTLRWEPPP
3D structure
PDB8umo Structure of the murine CD94-NKG2A receptor in complex with Qa-1 b presenting an MHC-I leader peptide.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 I24 E63 K66 M70 N73 N77 T80 Y84 W97 Y99 E116 W133 S143 K146 E152 Q155 Q156 Y159 W167 Y171 Y7 I24 E63 K66 M70 N73 N77 T80 Y84 W97 Y99 E116 W133 S143 K146 E152 Q155 Q156 Y159 W167 Y171
External links
PDB RCSB:8umo, PDBe:8umo, PDBj:8umo
PDBsum8umo
PubMed38158698
UniProtP06339|HA15_MOUSE H-2 class I histocompatibility antigen, D-37 alpha chain (Gene Name=H2-T23)

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