Structure of PDB 8ukz Chain A

Receptor sequence
>8ukzA (length=376) Species: 2094022 (Micromonospora sp. MW-13) [Search protein sequence]
YDPLAPSVIADPYPFYRKLRETNTVHWHEFLDSWVVTGYAECRQVLGDTT
NFGSDFRRIDVEIPDTQLSVQSLDPPEHGAIRHLLVSALHEQPLSTVRQQ
FAAIAAQHLAELSGQPGTVDLVSRFARPVALRTITAFLGVPPPDGAGFEQ
WSNAIVRSMDAGIEPARAEPGNQARAELSRLVTHWLAEADERGFVGAARR
AAVPAAVLANSLRAVLHAGYASVSRLLGGVLARLVRHPELLAGPATRDAD
EALVDELIRLDGPVQADARVCVRDQPVGAQLVRRGDVLVLFIAAANRDPA
VFPDPDAVRLTRRRGLHLAFGRGAHACLGAGLATLQLREVLGALRAGGLR
LAPAGPAAYEPTATLRGLAELPVSVR
3D structure
PDB8ukz Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A V83 H91 R95 G236 S239 P280 D284 R286 A336 F337 H342 C344 G346 V70 H78 R82 G219 S222 P263 D267 R269 A319 F320 H325 C327 G329
BS02 TFA A L102 L107 G348 L349 L89 L94 G331 L332
BS03 TFA A R188 R230 A231 R175 R213 A214
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0008395 steroid hydroxylase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0036199 cholest-4-en-3-one 26-monooxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0006707 cholesterol catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8ukz, PDBe:8ukz, PDBj:8ukz
PDBsum8ukz
PubMed
UniProtA0A3E2YLT4

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