Structure of PDB 8uiv Chain A

Receptor sequence
>8uivA (length=375) Species: 160488 (Pseudomonas putida KT2440) [Search protein sequence]
GRQKIAIVGAGLGGAAAATLLQQAGFDVEVFEQAPAFTRLGAGIQIGPNV
MKIFRRMGLEQKLELMGSHPDFWFSRDGNTGDYLSRIPLGEFARREYGAA
YITIHRGDLHALQIEAIQPGTVHFGKRLEKIVDEGDQVRLDFADGTHTVA
DIVIGADGIHSKIREELLGAEAPIYSGWVAHRALIRGVNLAQHADVFEPC
VKWWSEDRHMMVYYTTGKRDEYYFVTGVPHEAWDFQGAFVDSSQEEMRAA
FEGYHPTVQKLIDATESITKWPLRNRNPLPLWSRGRLVLLGDACHPMKPH
MAQGACMAIEDAAMLTRCLQETGLSDHRTAFALYEANRKERASQVQSVSN
ANTWLYSQEDPAWVYGYDLYGQQLE
3D structure
PDB8uiv Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights.
ChainA
Resolution1.511 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.114: 6-hydroxynicotinate 3-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A V10 G11 G15 E34 Q35 I46 Q47 R108 R129 L130 A158 D159 G160 R184 G293 D294 P301 A304 G306 A307 C308 V8 G9 G13 E32 Q33 I44 Q45 R106 R127 L128 A156 D157 G158 R182 G291 D292 P299 A302 G304 A305 C306
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8uiv, PDBe:8uiv, PDBj:8uiv
PDBsum8uiv
PubMed38104959
UniProtQ88FY2|6HN3M_PSEPK 6-hydroxynicotinate 3-monooxygenase (Gene Name=nicC)

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