Structure of PDB 8uf6 Chain A

Receptor sequence
>8uf6A (length=268) Species: 10090 (Mus musculus) [Search protein sequence]
KWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQREKFLRAHP
CVSDQELDELIQQIVAAINAGSHWDLGSSFFFAGTVITTIGFGNISPRTE
GGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQ
TKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSALDAIYFVVITLTTIG
FGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVIAKKT
KEAVGEFRAHAAEWTANV
3D structure
PDB8uf6 Structure of Trek-1(K2P2.1) with ML336
ChainA
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 WRZ A S131 F134 F145 V258 A259 G260 K271 W275 S78 F81 F92 V205 A206 G207 K218 W222
BS02 16C A Y57 I60 I299 A300 Y15 I18 I246 A247
External links
PDB RCSB:8uf6, PDBe:8uf6, PDBj:8uf6
PDBsum8uf6
PubMed
UniProtP97438|KCNK2_MOUSE Potassium channel subfamily K member 2 (Gene Name=Kcnk2)

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