Structure of PDB 8uf5 Chain A

Receptor sequence
>8uf5A (length=839) Species: 1309 (Streptococcus mutans) [Search protein sequence]
NKIVTTRSNLYKKYNQVYDRSAQSFEHVDHYLTAESWYRPKYILKDGKTW
TQSTEKDFRPLLMTWWPSQETQRQYVNYMNAQLGINKTYDDTSNQLQLNI
AAATIQAKIEAKITTLKNTDWLRQTISAFVKTQSAWNSDSEKPFDDHLQN
GAVLYDNEGKLTPYANSNYRILNRTPTNQTGKKDPRYTADNTIGGYEFLL
ANDVDNSNPVVQAEQLNWLHFLMNFGNIYANDPDANFDSIRVDAVDNVDA
DLLQIAGDYLKAAKGIHKNDKAANDHLSILEAWSDNDTPYLHDDGDNMIN
MDNKLRLSLLFSLAKPLNQRSGMNPLITNSLVNRTDDNAETAAVPSYSFI
RAHDSEVQDLIRDIIKAEINPNVVGYSFTMEEIKKAFEIYNKDLLATEKK
YTHYNTALSYALLLTNKSSVPRVYYGDMFTDDGQYMAHKTINYEAIETLL
KARIKYVSGGQAMRNQQVGNSEIITSVRYGKGALKATDTGDRTTRTSGVA
VIEGNNPSLRLKASDRVVVNMGAAHKNQAYRPLLLTTDNGIKAYHSDQEA
AGLVRYTNDRGELIFTAADIKGYANPQVSGYLGVWVPVGAAADQDVRVAA
STAPSTDGKSVHQNAALDSRVMFEGFSNFQAFATKKEEYTNVVIAKNVDK
FAEWGVTDFEMAPQYVSSTDGSFLDSVIQNGYAFTDRYDLGISKPNKYGT
ADDLVKAIKALHSKGIKVMADWVPDQMYAFPEKEVVTATRVDKFGKPVEG
SQIKSVLYVADSKSSGKDQQAKYGGAFLEELQAKYPELFARKQISTGVPM
DPSVKIKQWSAKYFNGTNILGRGAGYVLKDQATNTYFNI
3D structure
PDB8uf5 Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E405 D411 N455 D933 E197 D203 N247 D725
BS02 WIJ A A452 N455 A244 N247
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8uf5, PDBe:8uf5, PDBj:8uf5
PDBsum8uf5
PubMed28729722
UniProtP08987|GTFB_STRMU Glucosyltransferase-I (Gene Name=gtfB)

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