Structure of PDB 8udc Chain A

Receptor sequence
>8udcA (length=397) Species: 7070 (Tribolium castaneum) [Search protein sequence]
KEEELEGVCAEIREAISKIKAQAYDADESRFESNPITLNDLSLGKPIAKG
TNGVVYSAKVKDDNKYPFALKMMFNYDIQSNSMEILKAMYRETVPARMYA
SNHDLNNWEIELANRRKHLPPHPNIVAIFSVFTDRNMSLFLLMKRYDCNL
QSFLSTAPSTRTSLLLLAQLLEGVAHMTAHGIAHRDLKSDNLLLDTSEPE
SPILVISDFGCCLADKTNGLSLPYTSAEMDKGGNTALMAPEIICQKPGTA
SVLNYSKADLWAVGAIAYEIFNCHNPFYGPSRLKNANYKEGDLPKLPDEV
PTVIQALVANLLKRNPNKRLDPEVAANVCQLFLWAPSTWLKPGLKVPTSG
EILQWLLSLTTKVLCEGYPEYLLISSFLCRAKLANVRNALHWIQENL
3D structure
PDB8udc Structural Characterization of a small-molecule inhibitor of PINK1, a precursor tool compound for the study of Parkinson's disease
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WCK A I168 A169 M294 Y297 D298 C299 S303 L344 D359 I47 A48 M143 Y146 D147 C148 S152 L193 D208
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8udc, PDBe:8udc, PDBj:8udc
PDBsum8udc
PubMed
UniProtD6WMX4|PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial (Gene Name=Pink1)

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