Structure of PDB 8uct Chain A

Receptor sequence
>8uctA (length=391) Species: 7070 (Tribolium castaneum) [Search protein sequence]
KEEELEGVCAEIREAISKIKAQYYDIDESRFESNPITLNDLSLGKPIAKG
TNGVVYSAKVKDDNKYPFALKMMFNYDIQSNSMEILKAMYRETVPARMYA
WEIELANRRKHLPPHPNIVAIFSVFTDRNMSLFLLMKRYDCNLQSFLSTA
PSTRTSLLLLAQLLEGVAHMTAHGIAHRDLKSDNLLLDTSEPESPILVIS
DFGCCLADKTNGLSLPYTSAEMDKGGNTALMAPEIICQKPGTASVLNYSK
ADLWAVGAIAYEIFNCHNPFYGPSRLKNANYKEGDLPKLPDEVPTVIQAL
VANLLKRNPNKRLDPEVAANVCQLFLWAPSTWLKPGLKVPTSGEILQWLL
SLTTKVLCEGTYPEYLLISSFLCRAKLANVRNALHWIQENL
3D structure
PDB8uct Characterization of a new family of PINK1 inhibitors
ChainA
Resolution2.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3YT A A169 M294 K295 R296 Y297 D298 D341 L344 D359 A48 M136 K137 R138 Y139 D140 D183 L186 D201
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8uct, PDBe:8uct, PDBj:8uct
PDBsum8uct
PubMed
UniProtD6WMX4|PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial (Gene Name=Pink1)

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