Structure of PDB 8uci Chain A

Receptor sequence
>8uciA (length=381) Species: 1343739 (Palaeococcus pacificus DY20341) [Search protein sequence]
MVSSYFKGILLNLGLDEERIEVLENKGGIVEDEFEGMRYLRLKDSARSLR
RGTVVFDEHNIILGFPHIKRVVQLENGIRRAFKRKPFYVEEKVDGYNVRV
AKIGEKILVFTRGGFVCPFTTERIEDFITLDFFKDYPNMVLCGEMAGPES
PYLVEGPPYVKEDIQFFLFDIQEKKTGRSLPVEERLKLAEEYGIPSVEVF
GLYDLSRIDELHALIDRLTKEKREGIVMKSPDMKKIVGYVTPYANINDIK
IGARIFFDLPHGYFMQRIKRLAFYLAERKIRGEEFDEYARALGKVLLEPF
VESIWDISSGDDEIAELFTVRVKKLETAHKMVTHFERLRLKIHIDDIEVL
DNGYWRITFKRVYPDATKEMRELWNGHAFVD
3D structure
PDB8uci Characterisation and Engineering of a Thermophilic RNA Ligase from Palaeococcus pacificus
ChainA
Resolution2.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.3: RNA ligase (ATP).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AMP A I68 R70 K92 V93 E144 F169 K229 I68 R70 K92 V93 E144 F169 K229
BS02 MG A D94 E155 D248 D94 E155 D248
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8uci, PDBe:8uci, PDBj:8uci
PDBsum8uci
PubMed38421610
UniProtA0A075LQ94

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