Structure of PDB 8uac Chain A

Receptor sequence
>8uacA (length=215) Species: 9606 (Homo sapiens) [Search protein sequence]
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSE
QNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY
NPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGI
YFEPDCSSEDMDHGVLVVGYGFESNKYWLVKNSWGEEWGMGGYVKMAKDR
RNHCGIASAASYPTV
3D structure
PDB8uac CATHEPSIN L IN COMPLEX WITH AC1115
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.15: cathepsin L.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 W28 A G23 C25 N66 G67 G68 M70 D162 G23 C25 N66 G67 G68 M70 D162
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8uac, PDBe:8uac, PDBj:8uac
PDBsum8uac
PubMed38181791
UniProtP07711|CATL1_HUMAN Procathepsin L (Gene Name=CTSL)

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