Structure of PDB 8u9j Chain A

Receptor sequence
>8u9jA (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
DNMASLIQRIARQASLTFREAPMQPGFPENLSKLKSLLTQLRAEDLNIAP
RKATLQPLPPNLPPVTYMHIYETDGFSLGVFLLKSGTSIPLHDHPGMHGM
LKVLYGTVRISCMDKLDAGGGQRPRALPPEQQFEPPLQPREREAVRPGVL
RSRAEYTEASGPCILTPHRDNLHQIDAVEGPAAFLDILAPPYDPDDGRDC
HYYRVLEPVASDLPREVWLLETPQADDFWCEGEPYPGPKVFP
3D structure
PDB8u9j Cobalt(II)-Substituted Cysteamine Dioxygenase Oxygenation Proceeds through a Cobalt(III)-Superoxo Complex.
ChainA
Resolution2.02 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE A H112 H114 H193 H92 H94 H173
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0047800 cysteamine dioxygenase activity
GO:0051213 dioxygenase activity
Biological Process
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8u9j, PDBe:8u9j, PDBj:8u9j
PDBsum8u9j
PubMed38941563
UniProtQ96SZ5|AEDO_HUMAN 2-aminoethanethiol dioxygenase (Gene Name=ADO)

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