Structure of PDB 8u8w Chain A

Receptor sequence
>8u8wA (length=297) Species: 1028307 (Klebsiella aerogenes KCTC 2190) [Search protein sequence]
HMVSHLRGVMPALLTPFDAQQNIDRASLRRLVRFNIEQGVDGVYVGGSTG
EAFVQSLSEREEVLEIVAEEAKGKITLIAHVGCVSTAESQQLAAAAKRYG
FDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGIPMVVYNIPALSGVKLTL
EQINQLVTLPGVGALKQTSGDLYQMEQIRRAHPELVLYNGYDEIFASGLL
AGADGGIGSTYNIMAWRYLGIVQALKEGDTAKAQQLQHECNKVIDLLVKV
GVFRGLKTVLHYMDVLSVPLCRKPFAPVEDKFQAELKALAQQLMQER
3D structure
PDB8u8w Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate and halides bound)
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.3.3: N-acetylneuraminate lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PYR A A11 G46 S47 T48 Y137 K165 A12 G47 S48 T49 Y138 K166
Gene Ontology
Molecular Function
GO:0008747 N-acetylneuraminate lyase activity
GO:0016829 lyase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0019262 N-acetylneuraminate catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u8w, PDBe:8u8w, PDBj:8u8w
PDBsum8u8w
PubMed
UniProtA0A0H3FJT8

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