Structure of PDB 8u8s Chain A

Receptor sequence

>8u8sA (length=278) Species: 1902 (Streptomyces coelicolor) [Search protein sequence]

ITARTAPAGGEVRHLKMYAEKLADGQMGYGFEKGKASVPGPLIEVNEGDT
LHIEFTNTMDVRASLHVHGLDYEISSDGTAMNKSDVEPGGTRTYTWRTHK
PGRRDDGTWRPGSAGYWHYHDHVVGTEHGTGGIRNGLYGPVIVRRKGDVL
PDATHTIVFNDMTINNRKPHTGPDFEATVGDRVEIVMITHGEFYHTFHMH
GHRWADNRTGILTGPDDPSRVIDNKITGPADSFGFQIIAGEGVGAGAWMY
HCHVQFHSDMGMVGLFLVKKPDGTIPGY

3D structure

PDB

8u8s Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.

Chain

Resolution

2.63 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CU	A	H231 C288 H293	H195 C252 H257
BS02	CU	A	H236 H287	H200 H251
BS03	CU	A	H234 H236	H198 H200
BS04	GLY	A	G151 Y152 V179 R180 D184 R244	G115 Y116 V143 R144 D148 R208
BS05	GLY	A	G151 Y152 W153 S268	G115 Y116 W117 S232
BS06	GLY	A	P43 E80 N82 R180	P7 E44 N46 R144
BS07	GLY	A	G70 A72	G34 A36
BS08	GLY	A	K261 D267	K225 D231
BS09	CU	A	H104 H156	H68 H120
BS10	GLY	A	R256 K261 I262	R220 K225 I226

Gene Ontology

	Molecular Function
GO:0005507	copper ion binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:8u8s, PDBe:8u8s, PDBj:8u8s
PDBsum	8u8s
PubMed	37926680
UniProt	Q9XAL8

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