Structure of PDB 8u5y Chain A

Receptor sequence
>8u5yA (length=697) Species: 9606 (Homo sapiens) [Search protein sequence]
RSWIQKVLEQIMDSPRQCVTPSEVVPVTVLAVQRYLLEDEPRDTVPKPPL
YCYDVTISDGVYQEKCYLDPSLNSLVYQNILKVGIQMRISRVSCLYNIGQ
GILCIDNVHCGETSDSISLETPFRNRAHQEKPERPLRGGKSHYLALWNNE
DPYGDIWLTDKQPEEHNFSDTKIISLSHLEMTWTNRRNFPALLVRILHKS
KLRYYGKPDKKMIEPYQTFLEVADSSGTVSVIMWNALCPEWYKSLRVGLV
LLLQDYSVKKSYPFRIQPVPVDPQIKLISTMEICLNLRDPPTNIIIIPEK
QVKPEWRLPKLNHRFTTRSELDDMPENCICDVIGLLVFVGRVQRSKKKEN
REDFWSYRWIHIADGTSEQPFIVELFSTSQPEIFENIYPMAYFVCTQLKV
VRNDNQVPKLLYLTTTNESGVFITGHRGQPYTYDAKVKNFIQWIRTKSDS
GEQKNMVIGGYYPYPPVPETFSKYSSSIKVESLLTAISEVRKEIEDLQYR
EQKRIAIQGIITAIKYIPHSSISDRWESQLWREKKFGLIDHLHYSRVYPE
SIPRKFMFEHRKFLSDQYNSQPAKYVPPEGRPPKLDDFKSARSLGHFEVT
ILGLNHEIAIDVAFLPMYCPEDIRTSQIDTLLTSMNYSCAYPQDTTGNDR
LPGPRAVAGDIIKAATELDRVHIVGILDICNLGNNKVEVYLHKIYSP
3D structure
PDB8u5y Structure of RADX and mechanism for regulation of RAD51 nucleofilaments
ChainA
Resolution3.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R248 Y250 K252 W279 K304 Y307 F309 N331 R333 K393 E394 R203 Y205 K207 W234 K259 Y262 F264 N286 R288 K348 E349
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006282 regulation of DNA repair
GO:2000042 negative regulation of double-strand break repair via homologous recombination
Cellular Component
GO:0005657 replication fork
GO:0005694 chromosome
GO:0016607 nuclear speck

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u5y, PDBe:8u5y, PDBj:8u5y
PDBsum8u5y
PubMed37786681
UniProtQ6NSI4|RADX_HUMAN RPA-related protein RADX (Gene Name=RADX)

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