Structure of PDB 8u3a Chain A

Receptor sequence
>8u3aA (length=284) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SCIDTCNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYF
NFFVYCLYMIIFTAAAYYRPVEGLPPYKLKNTVGDYFRVTGEILSVSGGV
YFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKE
YVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLV
FLFGFSTYNSLYSTCLELFKFTIGMGDLEFTFIILLLAYVILTYILLLNM
LIALMGETVNKIAQESKNIWKLQRAITILDTEKS
3D structure
PDB8u3a Structural basis of TRPV1 modulation by endogenous bioactive lipids.
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VPN A R409 H410 D509 S510 Y511 S512 L515 F543 A546 M547 T550 L553 R557 E570 I573 L574 Q700 R23 H24 D123 S124 Y125 S126 L129 F157 A160 M161 T164 L167 R171 E184 I187 L188 Q273
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8u3a, PDBe:8u3a, PDBj:8u3a
PDBsum8u3a
PubMed38698206
UniProtO35433|TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (Gene Name=Trpv1)

[Back to BioLiP]