Structure of PDB 8u0z Chain A

Receptor sequence
>8u0zA (length=260) Species: 13443 (Coffea arabica) [Search protein sequence]
FRLPYGERVRLAKNPTGKKLFEIMIQKETNLCLAADVATAAELLDIADKV
GPEICMLKTHVDILPDFTPDFGSKLRSIAEKHNFLIFEDRKFADIGNTVT
MQYEGGIFKILDWADIVNAHIVSGPGIVDGLKLKGLPRGRGLLLLAEMSS
SGNFAKGDYTAAAVKIAEGHSDFVIGFISVNPASWPSGPGNPALIHATPG
VQLAKGGDALGQQYNTPFSVISERGSDIIIVGRGIIKAANPAEVAREYRL
QGWDAYLLHC
3D structure
PDB8u0z Structural and functional properties of uridine 5'-monophosphate synthase from Coffea arabica.
ChainA
Resolution1.399 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.10: orotate phosphoribosyltransferase.
4.1.1.23: orotidine-5'-phosphate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 N A A255 D257 K279 H281 Q433 Y435 G453 R454 A34 D36 K58 H60 Q212 Y214 G232 R233
Gene Ontology
Molecular Function
GO:0004590 orotidine-5'-phosphate decarboxylase activity
Biological Process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0044205 'de novo' UMP biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8u0z, PDBe:8u0z, PDBj:8u0z
PDBsum8u0z
PubMed38184030
UniProtA0A6P6VUE3

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