Structure of PDB 8u0t Chain A

Receptor sequence
>8u0tA (length=675) Species: 249024 (Rhinolophus alcyone) [Search protein sequence]
TPEDLAKIFLDNFNSEAENLSHQSSLASWEYNTNISDENIQKMDEAGAKW
SDFYETQSKHAKNFSLEEIHNDTVKLQLQILQQSGSPVLSEDKSKRLNSI
LNAMSTIYSTGKVCRPNNPQECLLLEPGLDNIMGTSKDYNERLWAWEGWR
AEVGKQLRPLYEEYVVLKNEMARGYHYEDYGDYWRRDYETEGSPDLEYSR
DQLTKDVERIFAEIKPLYEQLHAYVRTKLMDTYPFHISPTGCLPAHLLGD
MWGRFWTNLYPLTVPFAQKPNIDVTDAMLNQTWDAKRIFKEAEKFFVSIG
LPHMTEGFWNNSMLTDPGDGRKVVCHPTAWDLGKGDFRIKMCTKVTMEDF
LTAHHEMGHIQYDMAYASQPYLLRNGANEGFHEAVGEVMSLSVATPKHLK
TMGLLSPDFLEDNETEINFLFKQALTIVGTLPFTYMLEKWRWMVFKGEIP
KEEWMTKWWEMKRKIVGVVEPVPHDETYCDPASLFHVANDYSFIRYYTRT
IFEFQFHEALCRIAKHDGPLHKCDISNSTDAGKKLHQMLSVGKSQPWTSV
LKDFVDSKDMDVGPLLRYFEPLYTWLKEQNRNSFVGWNTDWSPYADQSIK
VRWNNNEMYLFRSSVAYAMREYFLKTKNQTILFGEEDVWVSNLKPRISFN
FYVTSPRNLSDIIPRPEVEGAIRMS
3D structure
PDB8u0t Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.-.-
3.4.17.23: angiotensin-converting enzyme 2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H374 E402 H355 E383
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008241 peptidyl-dipeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u0t, PDBe:8u0t, PDBj:8u0t
PDBsum8u0t
PubMed37989312
UniProtA0A0N7IQX6

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