Structure of PDB 8u0k Chain A

Receptor sequence
>8u0kA (length=247) Species: 582419 (Thermococcus paralvinellae) [Search protein sequence]
HMIIIKLGGSVISDYSFHRHIVEQIAEEIAQFYPDESFILVHGGGSFGHP
NAREYKITEGLVGDVDRKRIGFSKTHQAMLKLNDLIIQTFLEKGLPAYSV
SSSSIFLLENKEVVYGELEILRKLLELKFIPVLFGDTAIALDKGIDILSG
DQIVSYLAKMLKPSKVIFLMDVDGIYDRNPKERDAKLIEELNVEEIRHLL
ESIGNKLREALKIAKHSEVYFINGKVKENLGKAIRGEKVGTRLRKLE
3D structure
PDB8u0k Ternary complexes of isopentenyl phosphate kinase from Thermococcus paralvinellae reveal molecular determinants of non-natural substrate specificity.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.26: isopentenyl phosphate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A I178 Y179 R181 P183 I217 K220 I175 Y176 R178 P180 I203 K206
BS02 4LR A G47 H52 G138 I150 S152 G153 G44 H49 G135 I147 S149 G150
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0102043 isopentenyl phosphate kinase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:8u0k, PDBe:8u0k, PDBj:8u0k
PDBsum8u0k
PubMed38333996
UniProtW0I5G2

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