Structure of PDB 8tzi Chain A

Receptor sequence
>8tziA (length=385) Species: 9606 (Homo sapiens) [Search protein sequence]
PQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNNSLSAIFN
NVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAILLVFLITAILVK
VQLDALPFFVITMIKIVLINSFGAILQGSLFGLAGLFPASYTAAIMSGQG
LAGFFASVAMICAIASGSELSESAFGYFITACAVIILTIICYLGLPRLEF
YRYYQQLKLSIKAILKKISVLAFSVCFIFTITIGMFPAVTVEVKSSIAGS
STWERYFIPVSCFLTFNIFDWLGRSLTAVFMWPGKDSRWLPSLVLARLVF
VPLLLLCNIKPRRYLTVVFEHDAWFIFFMAAFAFSNGYLASLCMCFGPKK
VKPAEAETAGAIMAFFLCLGLALGAVFSFLFRAIV
3D structure
PDB8tzi Rational ENT1 inhibition as a pathway for neuropathic pain relief
ChainA
Resolution2.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U00 A T25 L26 W29 N30 M33 T34 M84 L92 G154 Q158 A187 I304 F307 P308 F334 N338 L442 T19 L20 W23 N24 M27 T28 M53 L61 G123 Q127 A156 I233 F236 P237 F263 N267 L371
External links
PDB RCSB:8tzi, PDBe:8tzi, PDBj:8tzi
PDBsum8tzi
PubMed
UniProtQ99808|S29A1_HUMAN Equilibrative nucleoside transporter 1 (Gene Name=SLC29A1)

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