Structure of PDB 8tyg Chain A

Receptor sequence
>8tygA (length=405) Species: 126793 (Plasmodium vivax Sal-1) [Search protein sequence]
KDLLYKYKLYGDIDEYAYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGC
KNCGVHMENPFNLNNSKTSSILYCENEECPFKLNCVKGKCEYMQSYCEGS
QISGFYFSDVVSVVSYNNERVTFRKLMGCHMHEESLFLYQQATGVLGMSL
SKPQGIPTFVNLLFDNAPQLKQVFTICISENGGELIAGGYDPAYIVRALR
EAEKVVWENVTRKYYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHI
PEDLYNKLNYFFDILCIQDMNNAYDVNKRLKMTNESFNNPLVQFDDFRKS
LKSIIAKENMCVKIVDGVQCWKYLEGLPDLFVTLSNNYKMKWQPHSYLYK
KESFWCKGIEKQVNNKPILGLTFFKNRQVIFDIQKNRIGFVDANCPSHPT
HTRPR
3D structure
PDB8tyg Plasmodium vivax PMV-WM08 inhibitor complex
ChainA
Resolution1.64 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SKC A I78 D80 S83 Q137 H173 F180 Q183 D313 G315 S316 I35 D37 S40 Q94 H130 F137 Q140 D242 G244 S245
BS02 TEW A K195 R283 K284 Y285 Y286 K152 R212 K213 Y214 Y215
External links
PDB RCSB:8tyg, PDBe:8tyg, PDBj:8tyg
PDBsum8tyg
PubMed
UniProtA5K302|PLM5_PLAVS Plasmepsin V (Gene Name=PMV)

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