Structure of PDB 8tyf Chain A

Receptor sequence

>8tyfA (length=400) Species: 126793 (Plasmodium vivax Sal-1) [Search protein sequence]

KDLLYKYKLYGDIDEYAYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGC
KNCGVHMENPFNLNNSKTSSILYCENEECPFKLNCVKGKCEYMQSYCEGS
QISGFYFSDVVSVVSYNNERVTFRKLMGCHMHEESLFLYQQATGVLGMSL
SKPQGIPTFVNLLFDNAPQLKQVFTICISENGGELIAGGYDPAYIVREAE
KVVWENVTRKYYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHIPED
LYNKLNYFFDILCIQDMNNAYDVNKRLKMTNESFNNPLVQFDDFRKSLKS
IIAKENMCVKIVDGVQCWKYLEGLPDLFVTLSNNYKMKWQPHSYLYKKES
FWCKGIEKQVNNKPILGLTFFKNRQVIFDIQKNRIGFVDANCPSHPTHTR

3D structure

PDB

8tyf Plasmodium vivax PMX-XX inhibitor complex

Chain

Resolution

2.59 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	T0F	A	I78 D80 S83 S87 Q137 Y139 I145 L179 F180 Q183 V188 D313 G315 S316	I35 D37 S40 S44 Q94 Y96 I102 L136 F137 Q140 V145 D239 G241 S242

External links

PDB	RCSB:8tyf, PDBe:8tyf, PDBj:8tyf
PDBsum	8tyf
PubMed
UniProt	A5K302\|PLM5_PLAVS Plasmepsin V (Gene Name=PMV)

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