Structure of PDB 8ttu Chain A

Receptor sequence
>8ttuA (length=256) Species: 9606 (Homo sapiens) [Search protein sequence]
SDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFE
VISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEILLND
NDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCE
GYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWD
EMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELK
WRKEEY
3D structure
PDB8ttu Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
ChainA
Resolution2.36 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A D435 S436 R437 R438 L453 Q465 I467 R498 D163 S164 R165 R166 L181 Q193 I195 R226
External links
PDB RCSB:8ttu, PDBe:8ttu, PDBj:8ttu
PDBsum8ttu
PubMed39116126
UniProtQ96L92|SNX27_HUMAN Sorting nexin-27 (Gene Name=SNX27)

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