Structure of PDB 8ttg Chain A

Receptor sequence
>8ttgA (length=374) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
MNKQIFVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLVAAFALS
QMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVI
GGMSAGMVMPGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIGGFM
AEVSHRMPFYFAGALGILAFIMSIVLIHDPPQLLTKINWKVFITPVILTL
VLSFGLSAFQTLYSLYTADKVNYSPKDISIAITGGGIFGALFQIYFFDKF
MKYFSELTFIAWSLLYSVVVLILLVFANDYWSIMLISFVVFIGFDMIRPA
ITNYFSNIAGERQGFAGGLNSTFTSMGNFIGPLIAGALFDVHIEAPIYMA
IGVSLAGVVIVLIEKQHRAKLKEQ
3D structure
PDB8ttg NorA single mutant - E222Q at pH 7.5
ChainA
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A G59 T60 D63 P110 T113 G114 D118 L195 L196 F327 G330 L331 T334 G59 T60 D63 P110 T113 G114 D118 L183 L184 F315 G318 L319 T322
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ttg, PDBe:8ttg, PDBj:8ttg
PDBsum8ttg
PubMed38802368
UniProtP0A0J7|NORA_STAAU Quinolone resistance protein NorA (Gene Name=norA)

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