Structure of PDB 8ts0 Chain A

Receptor sequence
>8ts0A (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
GCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQ
HHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGG
EDCAHFTDDGRWNDDVCQRPYRWVCETEL
3D structure
PDB8ts0 Targeted protein degradation systems to enhance Wnt signaling.
ChainA
Resolution1.7 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D216 D243 E253 D254 D64 D91 E101 D102
BS02 CA A Q240 D242 E253 N265 D266 Q88 D90 E101 N113 D114
BS03 CA A V191 E197 E278 V39 E45 E126
External links
PDB RCSB:8ts0, PDBe:8ts0, PDBj:8ts0
PDBsum8ts0
PubMed38847394
UniProtP07306|ASGR1_HUMAN Asialoglycoprotein receptor 1 (Gene Name=ASGR1)

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