Structure of PDB 8trr Chain A

Receptor sequence
>8trrA (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFD
3D structure
PDB8trr T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4
ChainA
Resolution2.65 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Q9 E11 I31 A52 S53 F54 N62 V65 N69 I72 M73 Q7 E9 I29 A50 S51 F52 N60 V63 N67 I70 M71
External links
PDB RCSB:8trr, PDBe:8trr, PDBj:8trr
PDBsum8trr
PubMed39043656
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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