Structure of PDB 8trl Chain A

Receptor sequence
>8trlA (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFD
3D structure
PDB8trl T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4
ChainA
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Q9 E11 F22 A52 S53 F54 N62 V65 D66 N69 I72 Q7 E9 F20 A50 S51 F52 N60 V63 D64 N67 I70
External links
PDB RCSB:8trl, PDBe:8trl, PDBj:8trl
PDBsum8trl
PubMed39043656
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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