Structure of PDB 8tqg Chain A

Receptor sequence
>8tqgA (length=277) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QIDGFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGF
ERVEGSIEERAQQYVPKLIEMQGDGPYVLVGWSLGGVLAYACAIGLRRLG
KDVRFVGLIDAVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYE
QLEELDDEGQVRFVLDAVSQSGVQIPAGIIEHQRTSYLDNRAIDTAQIQP
YDGHVTLYMADRYHDDAIMFEPRYAVRQPDGGWGEYVSDLEVVPIGGEHI
QAIDEPIIAKVGEHMSRALGQIEADRT
3D structure
PDB8tqg Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JR0 A S1533 V1537 A1561 V1562 R1563 R1578 W1579 Y1582 Y1637 N1640 R1641 D1644 I1648 Y1663 A1667 F1670 Y1674 W1683 Y1686 S83 V87 A111 V112 R113 R128 W129 Y132 Y187 N190 R191 D194 I198 Y213 A217 F220 Y224 W233 Y236
Gene Ontology
Biological Process
GO:0009058 biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:8tqg, PDBe:8tqg, PDBj:8tqg
PDBsum8tqg
PubMed38577994
UniProtI6X8D2|PKS13_MYCTU Polyketide synthase Pks13 (Gene Name=pks13)

[Back to BioLiP]